Title III · Practice
Free MPJE practice questions, each answer explained
Below are 60 free MPJE® (Multistate Pharmacy Jurisprudence Examination) practice questions, each tagged federal rule or multistate principle and answered with a ruling plus a note on every option. None of them covers a single state's own law, so treat them as the federal and shared layer of a state exam.
Checked against NABP and federal sources on October 19, 2026.
Casebook · 60 cases · free, no sign-up
The casebook: 60 MPJE practice cases
0 of 60 answered · 0 correct
Which statement best describes the responsibility of a pharmacist-in-charge (PIC) for controlled substances in the pharmacy?
Choose A, B, C or D. The ruling lands here: verdict, reasoning, then each option annotated.
Keys: A–D answer · N next · P back
Docket closed
Docket
§ 1 How to work the casebook
The 60 cases are filed by the four areas of NABP's MPJE Competency Statements, the outline for exams given before Mar 1, 2027, and their counts follow its weights.
| Competency area | Share of the MPJE | Cases here |
|---|---|---|
| Area 1 · Licensure/Personnel | 22% | 13 |
| Area 2 · Pharmacist Practice | 33% | 20 |
| Area 3 · Dispensing Requirements | 24% | 14 |
| Area 4 · Pharmacy Operations | 21% | 13 |
From Mar 1, 2027 a new content outline with renamed domains takes over.
Source: NABP, MPJE Competency Statements, checked October 19, 2026
Step 1
Keep the mixed docket or pick an area
All areas interleaves the four areas; a chip narrows it to one. The numbered tiles show right and wrong answers and jump to any case.
Step 2
Commit once
Your first pick is final, as on the MPJE, where a confirmed answer cannot be changed. You can page back to reread a ruling. Keys A to D answer; N and P move.
Step 3
Read every note
The wrong options are where a federal floor gets passed off as your state's number, or a NAPLEX rule as an MPJE one.
Step 4
Close the docket
You get correct answers per area, the split a failing MPJE score report also uses. A reload clears everything; nothing is saved.
§ 2 MPJE question formats, with a worked example of each
NABP's sample sheets, dated April 2026, show two MPJE formats: multiple-choice with one best answer, and multiple-response, marked Select ALL that apply
. The MPJE sample gives five options, the sample for the Uniform MPJE (UMPJE) three, and NABP says question types may be added or removed.
Multiple-choice: one best answer
Worked example. Pharmacies A and B do not share a real-time online database. Under federal rules, how many times may the original prescription information for a Schedule IV prescription be transferred between them for refills?
- A. Never: controlled substance refills cannot be transferred
- B. One time
- C. Two times
- D. As many times as refills remain
- E. Only with the prescriber's written approval
Multiple-response: select all that apply
Worked example. A patient asks you to fill part of a Schedule II prescription today and the rest later. Under 21 CFR 1306.13(b), which conditions must be met? (Select ALL that apply.)
- A. State law does not prohibit the partial fill
- B. The total of all partial fills does not exceed the quantity prescribed
- C. Remaining portions are filled no later than 30 days after the date the prescription was written
- D. The prescriber approves each partial fill by phone
- E. The remainder is filled within 72 hours of the first fill
Roman-numeral combinations (K-type)
Neither NABP sample sheet shows Roman-numeral combination items (I and II only
, known as K-type), so practice the two formats above first. Every casebook case is single best answer with four options: it trains the rules, while the examples above train the layouts.
§ 3 How to use practice questions: federal rules vs your state's law
NABP builds a separate MPJE for each jurisdiction and tells candidates to answer in terms of the prevailing laws of the state in which you are seeking licensure
. The exam does not label any question federal or state. The casebook does: 26 of the 60 cases rest on a federal rule and 34 on a multistate principle.
Federal rule
- Set by statute or regulation: the Controlled Substances Act, 21 CFR, the FD&C Act
- The same floor in every state
- Your state may add a stricter rule, and a state MPJE grades by that rule
Multistate principle
- A concept most boards share, such as the pharmacist-in-charge answering for compliance
- The numbers behind it (time limits, ratios, documentation) are set by each state
- Look the rule up in your state's pharmacy act and board rules
The tell If an answer turns on a number, find out who sets that number before you memorize it.
For that layer you need your board's pharmacy act and rules, read against the federal pharmacy law notes. The MPJE study guide lays both onto the four competency areas.
§ 4 Pre-MPJE vs free practice questions
The Pre-MPJE is NABP's own practice exam, and the one to schedule rather than repeat: its questions are state-specific, and you get one attempt per jurisdiction per year.
NABP's Pre-MPJE
- 40 questions, 50-minute limit
- $90 per attempt, bought through your NABP e-Profile
- State-specific questions, different for each jurisdiction
- Once a year per jurisdiction (the Pre-UMPJE twice a year)
- A total scaled score sent by email
This casebook
- 60 cases, no timer
- Free, no account
- Federal rules and multistate principles; no state's own law
- Restart as often as you like
- A ruling and a note on every option
The tell Build the federal floor here, then sit the Pre-MPJE after you have read your state's law, so its score reflects your state's questions.
§ 5 Practicing for the Uniform MPJE (UMPJE)
The UMPJE tests principles of state law uniform across adopting jurisdictions, alongside federal law. As of Oct 19, 2026, 13 jurisdictions had adopted it; how the Uniform MPJE differs has the dates and the score transfer.
The casebook covers federal law and multistate principles, which the UMPJE also tests, but it has not been checked against the UMPJE content outline. NABP's own UMPJE practice options are in the questions below.
§ 6 Sources for this page
§ 7 Questions candidates ask
How many questions do you need to get right to pass the MPJE?
NABP does not publish a number. The MPJE is reported as pass or fail only, against a standard set by a panel of pharmacy experts, and 20 of the 120 questions are unscored pretest items you cannot identify. The one hard count: you must answer at least 107 questions to receive a result.
Is the MPJE exam hard?
Its pass rate is lower than the NAPLEX's. In NABP's report of Feb 2, 2026, 74.5% of 2025 graduates of ACPE-accredited US schools passed the MPJE on the first attempt, against 86.8% on the NAPLEX; the class of 2015 managed 89.0%. Every question is graded by your state's law, so federal practice alone does not get you there.
How to pass the MPJE the first time?
Treat it as two jobs: the federal floor and shared concepts, weighted 22/33/24/21 across the four competency areas for exams before Mar 1, 2027, and then your state's pharmacy act and board rules, which no free federal bank covers.
Rehearse the conditions too: 120 questions in 2.5 hours, no going back, no scheduled breaks. A fail means a 30-day wait (longer if your state requires it) and a new $100 application plus $170 exam purchase, per NABP fees as of Oct 19, 2026. The pass rate and scoring page has the attempt limits.
Can you give me sample questions for the UMPJE?
NABP publishes a one-question UMPJE sample sheet (April 2026) and sells the Pre-UMPJE, which covers general principles of state law and can be taken twice a year. The casebook above covers federal law and multistate principles, which the UMPJE also tests, but it was not written against the UMPJE outline.
How do I interpret my Pre-MPJE score?
As a reading on your state's questions, not a pass prediction. The Pre-MPJE emails a total scaled score; NABP's page does not say which score means passing, and the MPJE itself reports pass or fail only. You get one per jurisdiction per year, so take it after studying your state's law, with time left to fix what it shows.